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Risk of Rain 2 Item Cheat Sheet: Quick Boost Guide

Locus Leo. by Locus Leo.
November 21, 2025
Risk of Rain 2 Item Cheat Sheet
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Risk of Rain 2 Item Cheat Sheet: Get quick boosts, key synergies and smart item tips to power your runs and improve every gameplay session.

If you’ve ever found yourself in the middle of a chaotic late-game run, frantically trying to remember whether Ukulele chains better with multi-hit abilities or if AtG Missiles scale with burst damage, you’re definitely not alone. I’ve been there too… staring at a glowing item drop, desperately wishing the game would whisper, “Hey, this is actually good for your build.” That constant mid-run confusion is exactly why so many of us search for a Risk of Rain 2 item cheat sheet or a Comparison Spreadsheet, hoping for a quick, reliable reference. But the problem is that most cheat sheets online are either outdated, oversimplified, or missing the deeper mechanics that actually matter during real gameplay.

So today, I’m putting everything together… years of personal gameplay experience, deep research into proc coefficients, hidden interactions, Void item conversions and essential synergies… to create a guide that not only serves as a risk of rain 2 item cheat sheet, but also helps you understand why certain items shine in different scenarios. Think of this as the cheat sheet you wish you had the first time you tried looping.

Why a Cheat Sheet Matters More Than You Think

Back when I first started playing Risk of Rain 2, I thought rarity alone determined an item’s value. Legendary? Instant pickup. White item? Meh, whatever. But after countless runs (and many painful deaths), I realized the real key is understanding proc coefficients, trigger types and synergy behaviors.

 

A solid risk of rain 2 item cheat sheet doesn’t just list items. It helps you understand how the game secretly calculates damage, procs, healing, crit behavior and multi-hit scaling. Once you get these mechanics, every pickup becomes a strategic decision rather than a “hope for the best” moment.

Understanding Proc Coefficients (The Hidden MVP)

If you’ve played long enough, you’ve noticed that some skills trigger procs constantly, while others barely spark a missile or lightning chain. The reason? Proc coefficients, a hidden multiplier assigned to every ability. A 1.0 coefficient means full proc chance. A 0.5 coefficient means half. And a 0.0 coefficient means… Well, no process at all.

 

This is why Commando’s rapid-fire primary triggers more chains than Loader’s big punches. And why something like Ukulele feels insane on multi-hit characters but underwhelming on others. A good risk of rain 2 item cheat sheet should always highlight which items depend on proc behavior, because it drastically affects your build.

Trigger Types: The Foundation of Smart Item Picking

Items in Risk of Rain 2 can be grouped by how they activate, not just by rarity. Understanding this helps you build smoother, more synergistic item sets.

1. On-Hit Items

These rely heavily on proc coefficients. Think Ukulele, Tri-Tip Dagger, AtG Missile. They thrive with survivors that attack fast or hit multiple times.

2. On-Kill Items

Will-o’-the-Wisp, Gasoline and similar items shine when you’re clearing hordes. These scale incredibly well with Artifacts like Sacrifice.

3. Crit-Based Items

Lens-Maker’s Glasses and Harvester’s Scythe can create insane sustain loops once you reach 100% crit. A smart risk of rain 2 item cheat sheet should note that 10 stacks of Glasses typically secure a full crit build.

4. Passive Items

These provide stable, reliable boosts… Tougher Times, Soldier’s Syringe and similar mainstay pickups. Some of these have effective caps.

5. Utility Items

Energy Drink, Paul’s Goat Hoof… small boosts that become huge when stacked.

Hidden Interactions Most Players Miss

A lot of cheat sheets skip over the deep mechanical quirks that dramatically change how items feel. But the real value of a strong risk of rain 2 item cheat sheet lies in explaining these lesser-known rules.

1. Some abilities NEVER proc items

Fuel Array and certain equipment attacks have 0.0 proc coefficients, meaning they don’t trigger any on-hit effects at all.

2. Chain effects have their own proc coefficients

Ukulele chains, for example, use a 0.2 coefficient, so they rarely cause further procs. This explains why proc loops don’t chain infinitely.

3. Effective caps are real

Tougher Times experiences diminishing returns. Crit chance caps around 100%. Healing items stop scaling beyond a certain point. Your cheat sheet should help you avoid overstacking.

4. Void items change how triggers work

Void transformations aren’t just upgrades… they often change the entire interaction pattern of the item. A proper risk of rain 2 item cheat sheet should clearly show Void conversions.

5. Artifacts completely reshape item value

Artifact of Sacrifice boosts on-kill items. Artifacts of Swarms make AoE effects better. Artifacts of Glass make healing items essential.

The Power of Synergy Cheat Sheets

Let me be honest… I used to think synergies were overrated. But the deeper I got into the game, the more I appreciated those tiny, elegant combinations that make a run feel unstoppable. Here are examples your risk of rain 2 item cheat sheet should highlight:

 

  • Harvester’s Scythe + Crit Items → near-immortal sustain
  • Ukulele + Attack Speed → lightning fireworks
  • AtG + Burst Abilities → boss-melting nukes
  • Will-o’-the-Wisp + High Mob Density → map-clearing explosions

 

These aren’t just combos… they’re the “aha!” moments that transform your entire run.

Why Formatting Matters (Searchers Want Speed, Not Essays)

Players landing on your blog don’t want to scroll through paragraphs before getting the info they need. The best way to present a risk of rain 2 item cheat sheet is:

 

  1. At the top: a downloadable PNG + mobile version
  2. Tables grouped by trigger type
  3. Short explanations, not long walls of text
  4. Color-coded rarity and trigger behavior
  5. A synergy mini-section for quick decisions
  6. A deeper mechanics section for hardcore players

 

This structure satisfies both beginners and veterans.

Key Takings:

  • Creating the perfect risk of rain 2 item cheat sheet is more than listing items… It’s about capturing the true depth of the game.

  • Once you understand proc behavior, trigger types, Void mechanics, synergy stacking and artifact influence, item decisions become instinctive.

  • And honestly, that’s when the game becomes the most fun.

  • The next time you’re mid-run, staring down an item printer and wondering what to do, you’ll finally have the clarity you’ve always wanted.

Additional Resources:

  1. Risk of Rain 2 Wiki – Items List: Complete list of all items, including effects, stacking mechanics, and useful in-game notes for quick reference.

  2. Pro Game Guides – Risk of Rain 2 Items Cheat Sheet:  User-friendly cheat sheet with practical recommendations for picking items during runs.

 

Locus Leo.

Locus Leo.

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